Kimmel has a guest, Pink has a crush and Depp has considerable anxiety. This is despite Johnny being the caliber of actor worthy of three Best Actor nominations. Mr. Depp is paid well to suspend our disbelief - yet when he's "just being himself" (e.g., out of character), he's just as human as the rest of us. Thus this interaction provides ample body language moments - a few of which are highlighted here as a tutorial.
With emotional states of significantly high embarrassment - it's very typical that both feet get placed flat on the floor (Pink had had her right leg crossed just prior to this) as one acquires a whole-body flexing, what is often called a "The Fetal Position".
Pink Covers her face partially with her hand - yet primarily with a portion of her top (which acts here as a hand-surrogate).
The "Eye Roll" is a conscious (deliberate) display of contempt (Most contempt expressions are subconsciously initiated) as well as indicating impatient dismissal.
Nonverbal Communication Analysis No. 3568: Hillary Clinton, (Low) Likability, Rapport (Destroying) and Body Language
Nonverbal Communication Analysis No. 3518: Donald Trump's Feminine and Beta Body Language
Nonverbal Communication Analysis No. 3552: Hillary Clinton, Body Language and variations on the Pistol Steeple
Nonverbal Communication Analysis No. 3546: Carly Fiorina's and Ted Cruz's Awkward Raised Hand Holding
Nonverbal Communication Analysis No. 3512: Emilia Clarke, "Me Before You" and Body Language
Nonverbal Communication Analysis No. 3479: Vicente Fox regarding Donald Trump's Proposed Wall - ‘I’m not going to pay for that F***ing wall!'
Nonverbal Communication Analysis No. 3389: Vladimir Putin and Barack Obama meet in Paris - Body Language Faux Pas
Nonverbal Communication Analysis No. 3387: Daniel Radcliffe, James McAvoy, The Graham Norton Show and Body Language